Multiple sclerosis (MS), Sjogren’s syndrome (SS), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), type 1 diabetes (T1D), others.
Solid Tumor Indications:
Hepatocellular carcinoma (HCC), non-small cell lung cancer (NSCLC), colorectal cancer (CRC), others.
ABS-066 is a splicing-modulating antisense oligonucleotide that reduces the expression of sIL7R by correcting the alteration in alternative splicing that produces it.
ABS-2005 is the first monoclonal antibody that specifically inhibits sIL7R while sparing the membrane-bound IL7R.
ABS-001 is a splicing-modulating antisense oligonucleotide that enhances the expression of sIL7R by increasing the splicing alteration that produces it.